Found 10 matching trials
FLT3 Ligand, CD40 Agonist Antibody, and Stereotactic Radiotherapy PHASE1 The purpose of this study is to test a new way of treating the most common ...
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Albert Einstein College of Medicine
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CD40 Agonist, Flt3 Ligand, and Chemotherapy in HER2 Negative Breast Cancer PHASE1 This research study is being done to find out if the immunotherapy drugs ca...
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University of Chicago Comprehensive Cancer Center
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A Study of CDX-1140 (CD40) as Monotherapy or in Combination in Patients With Advanced Malignancies PHASE1 This is a study to determine the maximum tolerated dose (MTD) for CDX-1140 ...
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HonorHealth Research Insititute
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FLT3 Ligand Immunotherapy and Stereotactic Radiotherapy for Advanced Non-small Cell Lung Cancer PHASE2 Based on promising data from our laboratory demonstrating synergy between a...
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Montefiore Medical Center
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In Situ Immunomodulation With CDX-301, Radiation Therapy, CDX-1140 and Poly-ICLC in Patients w/ Unresectable and Metastatic Solid Tumors PHASE1 This phase I trial evaluates the safety and effectiveness of in situ immuno...
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Active Not Recruiting
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Los Angeles General Medical Center
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A Vaccine (CDX-1401) With or Without a Biologic Drug (CDX-301) for the Treatment of Patients With Stage IIB-IV Melanoma PHASE2 This phase II trial studies the effect of a vaccine called CDX-1401 given w...
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University of Chicago Comprehensive Cancer Center
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In Situ Vaccine for Low-Grade Lymphoma: Combination of Intratumoral Flt3L and Poly-ICLC With Low-Dose Radiotherapy PHASE1 Our recent trials combining local radiotherapy with intratumoral administra...
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Icahn School of Medicine at Mount Sinai
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A Safety and Tolerability Study of CDX-301 With or Without Plerixafor for Stem Cell Mobilization in Matched Related Allogeneic Donor/Recipient Sibling Transplant Pairs PHASE2 This is an open-label, multicenter, prospective pilot study of CDX-301 with...
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UCLA Medical Center
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A Study to Evaluate CDX-301 (rhuFlt3L) in Healthy Volunteers PHASE1 CDX-301 is a protein that stimulates the growth of bone marrow stem cells a...
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Rockefeller University
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Vaccination With Flt3L, Radiation, and Poly-ICLC PHASE1 This is a combination of 4 therapies, three of which are used to treat a si...
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Icahn School of Medicine at Mount Sinai
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